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Program

Session 44   Poster Session
DC-SIGN and Dendritic Cells
4:30-6:30 pm
4E-F

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244-T. Identification of 2 Distinct Rhesus DC-SIGN Isoforms and Their Potential Roles in Lentiviral Transmission
Z. Chen *, Y. Huang, X. Zhao, L. Ba, A. Gettie, W. Zhang, B. Hu, and D. Ho
Aaron Diamond AIDS Res. Ctr., Rockefeller Univ., New York, NY
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245-T.
Functional Characterization of Mouse Monoclonal Antibodies Specific for DC-SIGN or DC-SIGNR
F. Baribaud*1, S. Pöhlmann1, G. Leslie1, D. Ghavimi1, J. Hoxie1, F. Mortari2, and R. W. Doms1
1Univ. of Pennsylvania, Philadelphia and 2R&D Systems, Minneapolis, MN
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246-T. Antibody Blocking of DC-SIGN/DC-SIGNR Interaction with HIV and Ebola Glycoproteins
S. Pöhlmann*1, F. Baribaud1, G. Leslie1, K. Strecker1, F. Mortari2, P. Bates1, and R. W. Doms1
1Univ. of Pennsylvania, Philadelphia and 2R&D Systems, Minneapolis, MN
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247-T. DC-SIGN and DC-SIGNR Bind Ebola Glycoproteins and Enhance Infection of Macrophages and Endothelial Cells
S. Pöhlmann*1, G. Simmons1, J. Reeves1, C. Grogan2, L. Vandenberghe1, F. Baribaud1, R. Netter1, J. Riley1, P. Bates1, and R. W. Doms1
1Univ. of Pennsylvania, Philadelphia and 2USAMRIID, Ft. Detrick, Frederick, MD
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248-T.
Peptide Mimics of DC-SIGN-Binding Glycan Structures on HIV gp120
S.V. Su* and B. Lee
Univ. of California, Los Angeles
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249-T. Increased Binding to DC-SIGN Correlates with Enhanced Transmission of R5-SHIVSF162P3 but not X4-SHIVSF33A
J. Lue*, M. Hsu, Z. Chen, D. Yang, and C. Cheng-Mayer
Aaron Diamond AIDS Res. Ctr., Rockefeller Univ., New York, NY
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250-T.
Clinical Relevance of Tandem-Repeat Polymorphisms in the Genetic Sequence of L-SIGN, a Novel HIV-Transreceptor
M. Lichterfeld*, H. D. Nischalke, J. Söhne, N. Quirishi, T. Sauerbruch, U. Spengler, and J. K. Rockstroh
Univ. of Bonn, Germany
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251-T.
Role of Macrophage Mannose Receptor in the Binding and Transmission of HIV-1
D. G. Nguyen* and J. E. K. Hildreth
Johns Hopkins Univ. Sch. of Med., Baltimore, MD
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252-T. Defects in Number and Surface Expression of Co-Stimulatory Molecules on CD11c+ and CD11c- Blood Dendritic Cells in HIV-1-Infected Individuals
M. A. Barron*, N. Blyveis, B. Palmer, S. MaWhinney, and C. C. Wilson
Univ. of Colorado Hlth. Sci. Ctr., Denver
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253-T.
Dendritic Cell Numbers and Function in an HIV-1-Infected Ugandan Population
G. Jones*1, P. Amjadi1, C. Watera2, J. Morlese1, P. Kaleebu2, J. Whitworth2, F. Gotch1, and J. Gilmour1
1Imperial Coll. of Sci. Technology and Med., London, UK and 2Med. Res. Council, Uganda Virus Res. Inst., Entebbe
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254-T.

Susceptibility of Plasmacytoid Dendritic Cell Precursors (preDC2) to HIV-1 Infection and Their Immunological Responses
A. Yonezawa*, T. Hori, A. Takaori, N. Kadowaki, T. Kitawaki, R. Morita, and T. Uchiyama
Kyoto Univ., Japan
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255-T.
Impaired Function of Isolated Blood Myeloid and Plasmacytoid Dendritic Cells from HIV-1-Infected Patients
H. Donaghy*1, B. Gazzard2, F. Gotch1, and S. Patterson1
1Imperial Coll. of Sci., Technology, and Med.; and 2Chelsea and Westminster Hosp., London, UK
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256-T. Expression of CXCR4 and SDF-1 in Lymphocytes and Dendritic Cells
M. Bermejo*1, J. Martin-Serrano, J. L. de Pablos2, J. M. Alonso1, C. Gamallo3, F. Arenzana-Seisdedos4, and J. Alcami1
1Inst. de Salud Carlos III, Majadahonda, Spain; 2Hosp. 12 de Octubre; 3Hosp. de la Princesa, Madrid, Spain; and 4Pasteur Inst., Paris, France
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257-T. Differential Depletion and Reconstitution on Therapy of the Dendritic Cell Repertoire in Circulating Blood of HIV+ Individuals
J. Chehimi1, D. Campbell2, L. Azzoni1, D. Bacheller2, G. Jerandi1, S. Black3, K. Mounzer3, J. Shull3, J. Kostman3,4, and L. J. Montaner*1
1Wistar Inst.; 2Children's Hosp.; 3Philadelphia FIGHT; and 4Univ. of Pennsylvania, Philadelphia
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